Well Referenced

Tag: atherosclerotic cardiovascular disease

Glycemia and Atherosclerotic Cardiovascular Disease: Exploring the Gap Between Risk Marker and Risk Factor

This review examines the relationship between glycemia and atherosclerotic cardiovascular disease (ASCVD), evaluating whether hyperglycemia serves merely as a risk marker or as a causative risk factor. Epidemiological evidence indicates that various glycemic indices (fasting plasma glucose, postprandial glucose, HbA1c) are associated with increased ASCVD risk, even in prediabetic states.

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June 26, 2025 No Comments

Statins for primary prevention of cardiovascular events and mortality in old and very old adults with and without type 2 diabetes: retrospective cohort study

This retrospective cohort study analyzed data from 46,864 individuals aged 75 and older without clinically recognized atherosclerotic cardiovascular disease (CVD) to evaluate the impact of statin therapy on primary prevention. Over a median follow-up of 5.6 years, statin use did not significantly reduce CVD events or all-cause mortality in those

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June 26, 2025 No Comments

Ten-year association of coronary artery calcium with atherosclerotic cardiovascular disease (ASCVD) events: the multi-ethnic study of atherosclerosis (MESA)

This cohort study from the Multi-Ethnic Study of Atherosclerosis (MESA) evaluated the association between coronary artery calcium (CAC) scores and the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) events in 6,783 participants from diverse ethnic backgrounds. The findings demonstrated that individuals with CAC scores of 0 had ASCVD event rates

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June 26, 2025 No Comments

Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St. Francis Heart Study randomized clinical trial

This randomized controlled trial evaluated the effects of atorvastatin (20 mg daily), vitamin C (1 g daily), and vitamin E (1,000 U daily) on coronary artery calcification and cardiovascular events in 1,005 asymptomatic adults aged 50 to 70 with elevated coronary calcium scores. Over a mean follow-up of 4.3 years,

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June 26, 2025 No Comments