Well Referenced

Tag: wound healing

Topical L-thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?

This review explores the potential of topical L-thyroxine (T4) in dermatology, highlighting its roles in skin physiology, wound healing, and hair growth. It discusses the mechanisms by which T4 influences epidermal and hair follicle functions, including modulation of keratin expression, mitochondrial activity, and stem cell behavior. The article emphasizes the

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June 26, 2025 No Comments

Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data

This 2018 review by Pickart and Margolina explores the multifaceted biological activities of the GHK-Cu peptide (glycyl-L-histidyl-L-lysine bound to copper). GHK-Cu modulates gene expression, upregulating genes associated with tissue repair and downregulating those linked to inflammation and cancer progression. It promotes collagen and elastin synthesis, enhances skin firmness, reduces wrinkles,

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June 26, 2025 No Comments

Hyperbaric oxygen therapy in radionecrotic lesions

This 1982 study investigated the application of hyperbaric oxygen therapy (HBOT) in treating radionecrotic lesions resulting from radiation therapy. HBOT involves administering 100% oxygen at elevated atmospheric pressures to enhance tissue oxygenation, promote angiogenesis, and facilitate healing in hypoxic tissues. The study reported that HBOT led to significant improvements in

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June 26, 2025 No Comments

Platelet-rich fibrin matrix for facial plastic surgery

This 2012 review article discusses the application of autologous platelet-rich fibrin matrix (PRFM) in facial plastic surgery. PRFM is utilized for volume augmentation, fat transfer supplementation, and as an adjunct to open surgical procedures. The article highlights PRFM’s role in enhancing wound healing and tissue regeneration due to its sustained

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June 26, 2025 No Comments

Platelet Preparations for Use in Facial Rejuvenation and Wound Healing: A Critical Review of Current Literature

This 2024 critical review evaluates the efficacy of platelet-based therapies—such as platelet-rich plasma (PRP) and platelet-rich fibrin matrix (PRFM)—in facial rejuvenation and wound healing. The authors analyze various studies, highlighting the potential benefits of these treatments in promoting tissue regeneration and aesthetic improvement. However, they also emphasize the need for

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June 26, 2025 No Comments

Nutritional Interventions for Preventing and Treating Pressure Ulcers

This 2024 Cochrane systematic review evaluated the effectiveness of nutritional interventions in preventing and treating pressure ulcers. The review included 32 randomized controlled trials with a total of 10,784 participants. Findings suggest that energy, protein, and micronutrient supplements may slightly increase the number of healed pressure ulcers compared to standard

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June 26, 2025 No Comments

The Role of Anabolic Hormones for Wound Healing in Catabolic States

This comprehensive review examines the interplay between anabolic hormones, nutrition, and wound healing, particularly in catabolic states such as trauma, burns, and chronic illness. It highlights how deficiencies in key anabolic hormones—human growth hormone (HGH), insulin-like growth factor-1 (IGF-1), insulin, and testosterone—impair protein synthesis and lean body mass maintenance, leading

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June 26, 2025 No Comments

Far Infrared Radiation (FIR): Its Biological Effects and Medical Applications

This 2012 review by Vatansever and Hamblin discusses the therapeutic potential of far infrared radiation (FIR) within the 3–12 μm wavelength range. FIR has demonstrated beneficial biological effects, including enhanced microcirculation, accelerated wound healing, reduction of inflammation, and pain relief. FIR can be delivered via lamps, saunas, or fabrics embedded

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June 26, 2025 No Comments