This 2018 review by Pickart and Margolina explores the multifaceted biological activities of the GHK-Cu peptide (glycyl-L-histidyl-L-lysine bound to copper). GHK-Cu modulates gene expression, upregulating genes associated with tissue repair and downregulating those linked to inflammation and cancer progression. It promotes collagen and elastin synthesis, enhances skin firmness, reduces wrinkles,
