This review explores the potential therapeutic benefits of curcumin, the active compound in turmeric, highlighting its anti-inflammatory, antineoplastic, and antioxidant properties. Curcumin has shown promise in treating conditions such as dyspepsia, peptic ulcer, inflammatory bowel disease, rheumatoid arthritis, osteoarthritis, uveitis, orbital pseudotumor, and pancreatic cancer. Its mild side effects, including
This randomized controlled trial investigated the use of curcuminoids, compounds derived from turmeric, in patients with oral lichen planus (OLP), a chronic autoimmune condition affecting the oral mucosa. The study found that curcuminoid treatment significantly reduced OLP symptoms compared to baseline, with no major adverse effects reported, indicating good tolerability.
This systematic review and meta-analysis examined the anti-inflammatory effects of curcumin supplementation, incorporating data from 32 randomized controlled trials with 2,038 participants. The analysis showed significant reductions in several inflammatory markers, including C-reactive protein, interleukin-6, tumor necrosis factor-alpha, and interleukin-8, as well as an increase in interleukin-10. Curcumin supplementation also
This systematic review and meta-analysis examined the effects of curcumin/turmeric supplementation on inflammatory and oxidative stress markers across 66 randomized controlled trials. The results showed significant reductions in C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6), along with improvements in total antioxidant capacity (TAC), superoxide dismutase (SOD) activity,
This article examines the clinical pharmacology of curcumin, a compound found in turmeric, for treating inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease. It discusses curcumin’s potent anti-inflammatory, antioxidant, and immunomodulatory effects that help reduce inflammation and promote healing in IBD patients. Clinical studies indicate a 40-50% improvement
This review explores the potential clinical applications of curcumin, a polyphenol derived from turmeric, in preventing and diagnosing Alzheimer’s disease (AD). Curcumin exhibits antioxidant, anti-inflammatory, and neuroprotective properties that may help delay or prevent neurodegenerative diseases by interacting with β-amyloid plaques and tau proteins, key pathological markers of AD. Additionally,
