This 2013 narrative review examines the application of extracorporeal shock wave therapy (ESWT) in treating tendinopathy, focusing on the differences between focused (FSWT) and radial (RSWT) modalities. The review highlights the distinct physical characteristics of FSWT and RSWT, noting that FSWT generates pressure waves that converge at a specific depth,
This 2021 systematic review evaluated clinical studies on stem cell therapy (SCT) for erectile dysfunction (ED), highlighting its potential as a regenerative treatment. Various stem cell types—adipose-derived (ADSC), bone marrow-derived (BMSC), umbilical cord, and placental—have been administered primarily via intracavernosal injection. Clinical trials reported improvements in erectile function, with some
This 2012 review article discusses the application of autologous platelet-rich fibrin matrix (PRFM) in facial plastic surgery. PRFM is utilized for volume augmentation, fat transfer supplementation, and as an adjunct to open surgical procedures. The article highlights PRFM’s role in enhancing wound healing and tissue regeneration due to its sustained
This 2017 clinical trial evaluated the efficacy and safety of a single intradermal injection of autologous platelet-rich plasma (PRP) for facial wrinkle treatment. Seventeen subjects with varying types and grades of facial wrinkles, including nasolabial folds (NLFs), were enrolled. The study found a significant reduction in the mean Wrinkle Severity
This 2024 critical review evaluates the efficacy of platelet-based therapies—such as platelet-rich plasma (PRP) and platelet-rich fibrin matrix (PRFM)—in facial rejuvenation and wound healing. The authors analyze various studies, highlighting the potential benefits of these treatments in promoting tissue regeneration and aesthetic improvement. However, they also emphasize the need for
This review examines the therapeutic potential of growth hormone-releasing hormone (GHRH) analogs, including both agonists and antagonists, in various medical fields such as oncology, regenerative medicine, and metabolic disorders. GHRH agonists have shown promise in promoting tissue regeneration, improving cardiac function, and enhancing islet survival in diabetes, while GHRH antagonists
This study explored the use of ozone therapy in the treatment of bisphosphonate-related osteonecrosis of the jaw (BRONJ), a condition caused by bisphosphonates that can lead to jaw bone degeneration. Over five years, 131 BRONJ patients were treated with a combination of ozone therapy, minimally invasive surgery, and antibiotics. The
This systematic review published in Medical Gas Research (2020) analyzes 28 studies evaluating the efficacy of ozonated oil in treating various acute and chronic inflammatory skin conditions, such as burns, diabetic foot ulcers, and aphthous ulcers. The key findings show that ozonated oil exhibits strong antimicrobial, anti-inflammatory, and regenerative effects
This review examines the therapeutic effects of BPC 157, a stable gastric pentadecapeptide, on fistula healing in rat models. Originally identified as an anti-ulcer agent, BPC 157 remains stable in human gastric juice for over 24 hours and has shown consistent efficacy in promoting the healing of gastrointestinal fistulas. The
This study evaluated the effect of BPC 157, a pentadecapeptide, on muscle healing in rats with corticosteroid-induced muscle impairment. BPC 157 was administered either intraperitoneally or topically as a cream, and it significantly accelerated muscle recovery, overcoming the negative impact of corticosteroid treatment. The results showed restored muscle function, with
