Tag: thyroid function

Association between the oxidative balance score and thyroid function: Results from the NHANES 2007-2012 and Mendelian randomization study

This cross-sectional study analyzed data from 6,222 adults from NHANES (2007–2012) to investigate the relationship between the oxidative balance score (OBS)—a composite index reflecting dietary and lifestyle factors affecting oxidative stress—and thyroid function, focusing on free thyroxine (FT4) and total thyroxine (TT4). Using weighted multivariable linear regression, the study found

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Growth hormone administration stimulates energy expenditure and extrathyroidal conversion of thyroxine to triiodothyronine in a dose-dependent manner and suppresses circadian thyrotrophin levels: studies in GH-deficient adults

The study “Growth hormone administration stimulates energy expenditure and extrathyroidal conversion of thyroxine to triiodothyronine in a dose-dependent manner and suppresses circadian thyrotrophin levels: studies in GH-deficient adults” examines the effects of growth hormone (GH) therapy on metabolic processes and thyroid function in adults with GH deficiency. The findings indicate

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Insight Into Molecular Determinants of T3 vs T4 Recognition From Mutations in Thyroid Hormone Receptor α and β

The study “Insight Into Molecular Determinants of T3 vs T4 Recognition From Mutations in Thyroid Hormone Receptor α and β” explores the structural mechanisms underlying the different affinities of triiodothyronine (T3) and thyroxine (T4) for thyroid hormone receptors (TRs). Researchers identified a novel M256T mutation in a patient with resistance

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