Tag: therapeutic strategies

Arsenic Toxicity: Molecular Targets and Therapeutic Agents

This in-depth review outlines the molecular pathways affected by arsenic toxicity and surveys both conventional and emerging therapeutic strategies. Arsenic exposure—primarily via contaminated water and food—induces oxidative stress, mitochondrial dysfunction, epigenetic alterations, and DNA damage, contributing to carcinogenesis, cardiovascular disorders, and neurotoxicity. The review highlights the use of chelating agents

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Glutamine Supplementation as a Novel Metabolic Therapeutic Strategy for LIG3-Dependent Chronic Intestinal Pseudo-Obstruction

The 2025 study “Glutamine Supplementation as a Novel Metabolic Therapeutic Strategy for LIG3-Dependent Chronic Intestinal Pseudo-Obstruction” explores glutamine as a therapeutic approach for treating chronic intestinal pseudo-obstruction (CIPO) caused by LIG3 mutations. The study finds that glutamine supplementation improves intestinal motility, reduces symptoms such as bloating and constipation, and enhances

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