Well Referenced

Tag: Testosterone deficiency

Testosterone deficiency in women: etiologies, diagnosis, and emerging treatments

This article explores testosterone deficiency in women, its causes, diagnosis, and emerging treatments. Testosterone is essential for sexual function, cognitive health, and bone density, with deficiency linked to symptoms like sexual dysfunction, fatigue, and osteoporosis, especially in post-menopausal women or those with premature ovarian failure. The article reviews the potential

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June 26, 2025 No Comments

Testosterone Therapy in Men With Prostate Cancer

This systematic review evaluates the use of testosterone therapy (TTh) in men with prostate cancer (PCa), focusing on whether TTh increases the risk of disease progression. The review found that recent evidence suggests TTh does not elevate the risk of prostate cancer or lead to more aggressive disease, especially when

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June 26, 2025 No Comments

Symptomatic response rates to testosterone therapy and the likelihood of completing 12 months of therapy in clinical practice

This cohort study evaluates the symptomatic response and adherence to testosterone therapy (TTh) in men with testosterone deficiency. The study involved 127 men, with most reporting improvements in erectile function, libido, energy, and mood within 3 months. By 12 months, 63% of the participants continued therapy with sustained benefits. However,

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June 26, 2025 No Comments

Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men

This review discusses the negative impact of testosterone deficiency (TD) and 5α-reductase inhibitors (such as finasteride) on metabolic and sexual health in men. TD leads to increased fat mass, insulin resistance, metabolic syndrome, erectile dysfunction, and decreased quality of life. The use of 5α-reductase inhibitors, which block the conversion of

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June 26, 2025 No Comments

Patients with testosterone deficit syndrome and depression

This review explores the relationship between testosterone deficiency syndrome (TDS) and depression, highlighting that hypogonadal men often experience depressive symptoms and may benefit from testosterone replacement therapy (TRT). Certain subpopulations, including men with HIV/AIDS, severe testosterone deficiency, or SSRI-resistant depression, show a more pronounced response to TRT, possibly due to

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June 26, 2025 No Comments

Exogenous testosterone or testosterone with finasteride increases bone mineral density in older men with low serum testosterone

This 2004 randomized controlled trial investigated the effects of testosterone therapy, with or without finasteride, on bone mineral density (BMD) in older men with low serum testosterone levels. The study found that testosterone administration significantly increased BMD, suggesting that testosterone therapy may be beneficial for improving bone health and reducing

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June 26, 2025 No Comments

Androgens, health and sexuality in women and men

This article reviews the role of testosterone in sexual and somatic health for both men and women, emphasizing its impact when deficient. The review highlights the need for clinical awareness and appropriate treatment, recommending testosterone therapy based on individual diagnoses. Testosterone supplementation can improve sexual function and overall well-being. The

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June 26, 2025 No Comments

Benefits and Health Implications of Testosterone Therapy in Men With Testosterone Deficiency

Testosterone therapy (TTh) is an effective treatment for men with testosterone deficiency (TD), improving sexual function, bone density, metabolic health, and overall quality of life. It normalizes testosterone levels, enhancing energy, libido, and metabolic control. While generally safe, cardiovascular risks should be monitored. Various delivery methods, such as injections and

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June 26, 2025 No Comments

Diagnosis and Treatment of Testosterone Deficiency: Updated Recommendations From the Lisbon 2018 International Consultation for Sexual Medicine

The 2019 article “Diagnosis and Treatment of Testosterone Deficiency: Updated Recommendations From the Lisbon 2018 International Consultation for Sexual Medicine” provides revised clinical guidelines on testosterone deficiency (TD) and its treatment. The recommendations emphasize that symptoms correlate more closely with free testosterone levels than total levels, with treatment consideration for

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June 26, 2025 No Comments