Melatonin and Cancer Hallmarks
This 2018 review article explores melatonin’s multifaceted anticancer effects across the established hallmarks of cancer. Melatonin interferes with sustained proliferative signaling by inhibiting pathways such as HIF-1α, NF-κB, and PI3K/Akt, and modulates estrogen receptor activity. It promotes genomic stability through antioxidant activity, DNA repair enhancement, and telomerase inhibition. Melatonin induces
June 26, 2025
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