Well Referenced

Tag: systematic review

Safety and Serum Estradiol Levels in Hormonal Treatments for Vulvovaginal Atrophy in Breast Cancer Survivors: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis examined the safety and serum estradiol levels associated with hormonal treatments for vulvovaginal atrophy (VVA) in breast cancer survivors. The findings indicate that certain hormonal therapies lead to minimal increases in serum estradiol levels, remaining within safe thresholds, and effectively alleviating VVA symptoms such as

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June 26, 2025 No Comments

Efficacy and safety of transdermal testosterone in postmenopausal women with hypoactive sexual desire disorder: a systematic review and meta-analysis

A systematic review and meta-analysis published in Fertility and Sterility (2017) evaluated the efficacy and safety of transdermal testosterone therapy in postmenopausal women with hypoactive sexual desire disorder (HSDD). The study found that transdermal testosterone significantly improved sexual function in both naturally and surgically menopausal women, regardless of concurrent estrogen-progestin

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June 26, 2025 No Comments

Hormone Therapy, Mental Health, and Quality of Life Among Transgender People: A Systematic Review

This systematic review examined the psychological outcomes of gender-affirming hormone therapy (GAHT) in transgender individuals, focusing on its impact on quality of life (QOL), depression, anxiety, and suicide risk. The review, which included 20 studies, found that GAHT was associated with improvements in QOL, decreased depression, and reduced anxiety. However,

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June 26, 2025 No Comments

Blue-Light Therapy for Acne Vulgaris: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis evaluated the effectiveness of blue-light therapy in treating acne vulgaris, analyzing 14 randomized controlled trials with a total of 698 participants. The study found that while some trials reported significant investigator-assessed and patient-reported improvements, the mean differences in inflammatory and non-inflammatory lesion counts were not

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June 26, 2025 No Comments