Pharmacokinetics of oral and intravenous cannabidiol and its antidepressant-like effects in chronic mild stress mouse model
This 2019 animal study investigated the pharmacokinetics and antidepressant-like effects of cannabidiol (CBD) in mice subjected to chronic mild stress. The study found that a single intravenous dose of CBD had a half-life of 3.9 hours and oral bioavailability of only 8.6%, suggesting IV delivery may be more efficient. Both
June 26, 2025
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