This 2020 study by Wang et al. analyzed data from the Long Island Breast Cancer Study Project to assess the association between menopausal hormone therapy (MHT) use and long-term mortality outcomes. Among women with breast cancer, ever-users of MHT had a 23% lower risk of all-cause mortality (HR=0.77), a 31%
This population-based cohort study analyzed 282,969 five-year survivors of adolescent and young adult (AYA) cancers diagnosed between 1975 and 2011, using SEER registry data. Over four decades, 5-year post-survival all-cause mortality decreased from 8.3% to 5.4%, primarily due to reductions in primary cancer mortality (6.8% to 4.2%). Significant improvements were
This retrospective cohort study assessed the impact of body mass index (BMI) variation on recurrence risk in women with early-stage breast cancer. The analysis revealed that a BMI increase exceeding 5.71% post-diagnosis was significantly associated with higher recurrence rates. Additional factors linked to increased recurrence included age under 55 years,
This prospective cohort study evaluated 4,376 men diagnosed with clinically localized prostate cancer between 1997 and 2002, assessing the impact of BMI at diagnosis and subsequent weight changes on disease progression and mortality. Over the follow-up period, 14.6% experienced disease progression, 10.3% died from any cause, and 3.1% died from
This review examines sexual dysfunction in cancer patients and survivors, focusing on how cancer treatments like chemotherapy, radiation, and surgery can lead to significant sexual health issues such as vaginal dryness, erectile dysfunction, and decreased libido. It discusses various treatment strategies, including hormonal therapies, counseling, and medical interventions like lubricants,
This observational study assessed menopausal symptoms and treatment use in 169 postmenopausal breast cancer survivors, revealing that 62.3% experienced hot flushes, but only 26.6% used treatments. Aromatase inhibitor users reported more sexual dysfunction. Barriers to treatment included fear of recurrence, lack of symptoms, and medical advice. This highlights gaps in
