surgical oncology Archives - Well Referenced

Melanoma In Situ: A Critical Review and Re-Evaluation of Current Excision Margin Recommendations

This 2021 critical review assesses the sufficiency of current excision margin recommendations for melanoma in situ (MIS), focusing especially on lentigo maligna (LM), a subtype common on sun-damaged skin. Analyzing 31 non-randomized studies, the authors found that standard 5–10 mm margins frequently fail to achieve histologic clearance, particularly for LM

June 26, 2025 No Comments

Melanoma Trials That Defined Surgical Management: Overview of Trials That Established NCCN Margin Guidelines

This 2022 review outlines key clinical trials that have influenced the NCCN surgical margin guidelines for melanoma. It discusses the shift from historically wide excision margins to more evidence-based, conservative approaches that maintain oncologic safety while reducing morbidity. Trials comparing 1 cm versus 2 cm margins for intermediate-thickness melanomas (1–4

June 26, 2025 No Comments

Tag: surgical oncology

Melanoma In Situ: A Critical Review and Re-Evaluation of Current Excision Margin Recommendations

Melanoma Trials That Defined Surgical Management: Overview of Trials That Established NCCN Margin Guidelines