Melanoma In Situ: A Critical Review and Re-Evaluation of Current Excision Margin Recommendations

This 2021 critical review assesses the sufficiency of current excision margin recommendations for melanoma in situ (MIS), focusing especially on lentigo maligna (LM), a subtype common on sun-damaged skin. Analyzing 31 non-randomized studies, the authors found that standard 5–10 mm margins frequently fail to achieve histologic clearance, particularly for LM