Well Referenced

Tag: sexual medicine

The future is today: emerging drugs for the treatment of erectile dysfunction

This review explores emerging drug therapies for erectile dysfunction (ED), discussing both central regulators (clavulanic acid, dopamine and melanocortin receptor agonists) and peripheral regulators (novel PDE5 inhibitors, soluble and particulate guanylyl cyclase activators, rho-kinase inhibitors, and maxi-K channel openers). These emerging treatments offer the potential for individualized approaches tailored to

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June 26, 2025 No Comments

The potential role of intracavernosal injection of platelet-rich plasma for treating patients with mild to moderate erectile dysfunction: A GRADE-Assessed systematic review and meta-analysis of randomized controlled trials

This systematic review and meta-analysis evaluated the efficacy and safety of intracavernosal platelet-rich plasma (PRP) injections for treating mild to moderate erectile dysfunction (ED), analyzing three randomized controlled trials with 221 patients. The PRP group showed significant improvements in erectile function based on the International Index of Erectile Function-Erectile Function

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June 26, 2025 No Comments

Emerging drugs for the treatment of erectile dysfunction

This review article explores emerging pharmacological and regenerative therapies for erectile dysfunction (ED), including soluble guanylate cyclase (sGC) activators and stimulators, Rho-kinase inhibitors, melanocortin receptor agonists, gene therapy, and stem cell therapy. These treatments offer alternative mechanisms beyond phosphodiesterase type 5 (PDE5) inhibitors, potentially benefiting patients unresponsive to conventional ED

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June 26, 2025 No Comments

Evaluating the efficacy and safety of platelet-rich plasma injection for erectile dysfunction: a systematic review and meta-analysis of randomized controlled trials

This meta-analysis systematically reviewed three randomized controlled trials (RCTs) involving 230 patients to evaluate the efficacy and safety of platelet-rich plasma (PRP) injections for erectile dysfunction (ED). PRP treatment significantly improved erectile function, with patients showing a greater mean improvement in International Index of Erectile Function (IIEF) scores (MD, 2.99;

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June 26, 2025 No Comments

Summary of the recommendations on sexual dysfunctions in women

This article provides an update to the 2004 recommendations on diagnosing and managing female sexual dysfunction, developed by a multidisciplinary team of 186 experts from 33 countries. The recommendations emphasize the importance of comprehensive medical, sexual, and psychosocial assessments, and the need for evidence-based treatment strategies. A multidisciplinary approach is

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June 26, 2025 No Comments