Well Referenced

Tag: Randomized Controlled Trial

A double-blind, parallel-group, placebo-controlled, multicentre study of acetyl L-carnitine in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection

This randomized controlled trial evaluated the efficacy of acetyl-L-carnitine (ALC) in treating antiretroviral toxic neuropathy in HIV-1 patients through a multicenter, double-blind, placebo-controlled design. The study found that ALC significantly improved neuropathic symptoms compared to placebo, suggesting its potential as a therapeutic option to enhance quality of life and treatment

Read More »
June 26, 2025 No Comments

Double-blind, randomized, placebo-controlled crossover trial of alpha-lipoic acid for the treatment of fibromyalgia pain: the IMPALA trial

The study titled Double-blind, randomized, placebo-controlled crossover trial of alpha-lipoic acid for the treatment of fibromyalgia pain: the IMPALA trial, published in Pain (2021), investigated the efficacy of alpha-lipoic acid (ALA) in reducing pain among fibromyalgia patients. This randomized controlled trial found that ALA significantly reduced pain scores compared to

Read More »
June 26, 2025 No Comments

“Beet” the cold: beetroot juice supplementation improves peripheral blood flow, endothelial function, and anti-inflammatory status in individuals with Raynaud’s phenomenon

This randomized controlled trial investigated the effects of nitrate-rich beetroot juice supplementation on individuals with Raynaud’s phenomenon, a condition characterized by reduced blood flow to extremities. The study included 23 participants in a double-blind, randomized crossover design, assessing both acute and chronic (14-day) supplementation. Key findings showed increased peripheral blood

Read More »
June 26, 2025 No Comments

A double-blind, randomized, placebo-controlled trial of the effect of testosterone cream on the sexual motivation of menopausal hysterectomized women with hypoactive sexual desire disorder

This study evaluated the effectiveness of a 10 mg testosterone cream on sexual motivation in postmenopausal women with hypoactive sexual desire disorder. The results showed significant improvement in sexual desire and activity without adverse effects on mood or physical health. The treatment is safe, effective, and non-invasive for improving sexual

Read More »
June 26, 2025 No Comments