Well Referenced

Tag: probiotics

Effects of a Diet-Based Weight-Reducing Program with Probiotic Supplementation on Satiety Efficiency, Eating Behaviour Traits, and Psychosocial Behaviours in Obese Individuals

A double-blind, randomized, placebo-controlled trial involving 105 obese adults (45 men, 60 women) assessed the impact of Lactobacillus rhamnosus CGMCC1.3724 (LPR) supplementation over a 24-week period (12 weeks of weight loss followed by 12 weeks of maintenance). Participants consumed two capsules daily, each containing 10 mg of LPR (1.6×10^8 CFU),

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June 26, 2025 No Comments

Health supplements for allergic rhinitis: A mixed-methods systematic review

This 2020 mixed-methods systematic review assessed the efficacy and safety of various health supplements in managing allergic rhinitis. Analyzing 48 randomized controlled trials and 10 observational studies, the review found promising evidence for single supplements such as apple polyphenols, tomato extract, spirulina, chlorophyll c2, honey, conjugated linoleic acid, methylsulfonylmethane (MSM),

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June 26, 2025 No Comments

Intestinal Microbiota; Relevance to Obesity and Modulation by Prebiotics and Probiotics

This 2013 literature review analyzed 61 studies to explore the relationship between intestinal microbiota and obesity, focusing on the effects of prebiotics and probiotics. Findings indicate that obese individuals exhibit distinct gut microbial compositions compared to non-obese individuals, with alterations affecting energy homeostasis, lipid metabolism, and intestinal permeability. Interventions using

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June 26, 2025 No Comments

Intestinal microbiota in pathophysiology and management of irritable bowel syndrome

This 2014 review examines the role of intestinal microbiota in the pathophysiology and management of irritable bowel syndrome (IBS). It highlights that alterations in gut microbiota composition, known as dysbiosis, may contribute to IBS symptoms by affecting mucosal immunity, increasing epithelial permeability, and activating sensory-motor dysfunction. The review discusses potential

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June 26, 2025 No Comments

Probiotic strains and mechanistic insights for the treatment of type 2 diabetes

This 2017 review examines the role of specific probiotic strains, particularly from the Lactobacillus and Bifidobacterium genera, in managing type 2 diabetes (T2D). It highlights that alterations in gut microbiota composition are associated with T2D and that probiotics may offer therapeutic benefits by modulating this microbiota. The review emphasizes the

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June 26, 2025 No Comments

Gut Microbiota and Obesity: A Role for Probiotics

This 2019 review explores the interplay between gut microbiota and obesity, highlighting how dysbiosis—characterized by reduced microbial diversity and an increased Firmicutes-to-Bacteroidetes ratio—contributes to obesity development. The authors discuss the potential of probiotics to modulate gut microbiota composition, thereby influencing host metabolism, energy balance, and inflammatory responses. Evidence from animal

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June 26, 2025 No Comments

The use of probiotics in healthy volunteers with evacuation disorders and hard stools: a double-blind, randomized, placebo-controlled study

This double-blind, randomized, placebo-controlled study assessed the efficacy of two probiotic blends in managing evacuation disorders and hard stools among 300 healthy volunteers aged 24–71 years. Participants were divided into three groups: Group A received a placebo; Group B received a combination of Lactobacillus plantarum LP01 and Bifidobacterium breve BR03

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June 26, 2025 No Comments

Good Bug, Bad Bug: Breaking through Microbial Stereotypes

This 2018 commentary challenges the binary classification of microbes as strictly beneficial or harmful, proposing that microbial roles are highly context-dependent. Using Akkermansia muciniphila as a case study, the authors illustrate how a bacterium commonly linked to metabolic health can also be associated with disease under certain conditions. The article

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June 26, 2025 No Comments

Lactobacillus species: taxonomic complexity and controversial susceptibilities

This 2015 review discusses the taxonomic challenges and antibiotic susceptibility controversies surrounding Lactobacillus species. With over 170 species exhibiting phenotypic similarities, accurate identification often requires molecular methods. While generally considered non-pathogenic and used as probiotics, certain strains have been implicated in infections, particularly in immunocompromised individuals. The article highlights the

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June 26, 2025 No Comments