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Tag: pregnancy outcomes

MTHFR isoform carriers. 5-MTHF (5-methyl tetrahydrofolate) vs folic acid: a key to pregnancy outcome: a case series

This observational study explored the effects of 5-methyl tetrahydrofolate (5-MTHF) compared to synthetic folic acid in couples with MTHFR isoform mutations (C677T and A1298C), which are linked to fertility issues and recurrent fetal loss. It found that 5-MTHF supplementation might improve pregnancy outcomes by bypassing metabolic defects caused by the

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June 26, 2025 No Comments

The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations

This study investigated the effects of supplementation with methylfolate, vitamin B6, and vitamin B12 on plasma homocysteine levels and pregnancy outcomes in women with recurrent pregnancy loss (RPL) and MTHFR mutations. Sixteen women with RPL and confirmed MTHFR mutations were randomized to receive the supplements for a year, resulting in

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June 26, 2025 No Comments