Tag: peak systolic velocity

Long-term high-dose L-arginine supplementation in patients with vasculogenic erectile dysfunction: a multicentre, double-blind, randomized, placebo-controlled clinical trial

This 2022 multicenter, double-blind, randomized, placebo-controlled trial evaluated the effects of high-dose L-arginine (6 g/day) over 3 months in 98 men with vasculogenic erectile dysfunction (ED). L-arginine significantly improved International Index of Erectile Function-6 (IIEF-6) scores in both mild-moderate and severe ED groups. Peak systolic velocity (PSV) improvements were significant

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Safety and Efficacy of 2 Intracavernous Injections of Allogeneic Wharton’s Jelly-Derived Mesenchymal Stem Cells in Diabetic Patients with Erectile Dysfunction: Phase 1/2 Clinical Trial

This 2021 phase 1/2 clinical trial evaluated the safety and efficacy of two intracavernous injections of allogeneic Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) in 22 diabetic men with refractory erectile dysfunction (ED). The procedure was well-tolerated, with only minimal and transient adverse events such as redness and bruising at the

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Evaluating the efficacy and safety of platelet-rich plasma injection for erectile dysfunction: a systematic review and meta-analysis of randomized controlled trials

This meta-analysis systematically reviewed three randomized controlled trials (RCTs) involving 230 patients to evaluate the efficacy and safety of platelet-rich plasma (PRP) injections for erectile dysfunction (ED). PRP treatment significantly improved erectile function, with patients showing a greater mean improvement in International Index of Erectile Function (IIEF) scores (MD, 2.99;

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