mortality Archives - Well Referenced

Association of Wearable Device-Measured Vigorous Intermittent Lifestyle Physical Activity with Mortality

This prospective cohort study analyzed data from 25,241 non-exercising adults (mean age 61.8 years) in the UK Biobank to assess the impact of vigorous intermittent lifestyle physical activity (VILPA) on mortality. VILPA, characterized by brief bouts (1–2 minutes) of vigorous activity during daily life, was measured using wearable accelerometers. Over

June 26, 2025 No Comments

Association of Body Mass Index With Lifetime Risk of Cardiovascular Disease and Compression of Morbidity

This 2018 pooled analysis of 190,672 participants from 10 U.S. cohort studies assessed the relationship between BMI and lifetime risk of cardiovascular disease (CVD). Compared to individuals with normal BMI (18.5–24.9), overweight (BMI 25.0–29.9), obese (BMI 30.0–39.9), and morbidly obese (BMI ≥40.0) individuals had significantly higher lifetime risks of developing

June 26, 2025 No Comments

Body-Mass Index and Cause-Specific Mortality in 900,000 Adults: Collaborative Analyses of 57 Prospective Studies

This 2009 meta-analysis by the Prospective Studies Collaboration pooled data from 57 prospective studies involving 894,576 adults, primarily from Western Europe and North America. The study investigated the relationship between body mass index (BMI) and cause-specific mortality. Findings indicated that the lowest mortality risk was observed in individuals with a

June 26, 2025 No Comments

Adiposity and Risk of Decline in Glomerular Filtration Rate: Meta-analysis of Individual Participant Data in a Global Consortium

This 2019 individual participant data meta-analysis pooled data from over 5.4 million adults across 39 general population cohorts, 6 high cardiovascular risk cohorts, and 18 chronic kidney disease (CKD) cohorts spanning 40 countries. The study assessed associations between adiposity measures—body mass index (BMI), waist circumference, and waist-to-height ratio—and decline in

June 26, 2025 No Comments

Weight loss causes increased mortality: pros

This review article examines the paradoxical findings from observational studies indicating that weight loss in overweight individuals may be associated with increased long-term mortality, even after adjusting for confounding factors such as underlying diseases and hazardous behaviors. The author highlights the methodological challenges in distinguishing intentional from unintentional weight loss

June 26, 2025 No Comments

Bayesian Analysis of the Effect of Intentional Weight Loss on Mortality Rate

This study developed Bayesian latent-variable linear models to distinguish the effects of intentional weight loss (IWL) from unintentional weight loss (UWL) on mortality rates. Utilizing data from rodent caloric restriction studies, the researchers found that IWL was associated with increased lifespan, whereas UWL correlated with decreased lifespan. The methodology involved

June 26, 2025 No Comments

The obesity paradox and weight loss

This 2011 study investigated the relationship between weight changes and mortality in 3,834 men over a mean follow-up of 7 years. Findings revealed that weight loss was associated with higher all-cause mortality, while weight gain correlated with lower mortality compared to stable weight. Specifically, each pound of weight lost per

June 26, 2025 No Comments

Menopausal hormone therapy use and long-term all-cause and cause-specific mortality in the Long Island Breast Cancer Study Project

This 2020 study by Wang et al. analyzed data from the Long Island Breast Cancer Study Project to assess the association between menopausal hormone therapy (MHT) use and long-term mortality outcomes. Among women with breast cancer, ever-users of MHT had a 23% lower risk of all-cause mortality (HR=0.77), a 31%

June 26, 2025 No Comments

Mortality after bariatric surgery: analysis of 13,871 morbidly obese patients from a national registry

This 2007 retrospective analysis examined 13,871 bariatric procedures recorded in the Italian Society of Obesity Surgery’s national registry between 1996 and 2006. The overall 60-day mortality rate was 0.25%. Mortality varied significantly by procedure: 0.1% for adjustable silicone gastric banding (ASGB), 0.15% for vertical banded gastroplasty (VBG), 0.54% for gastric

June 26, 2025 No Comments

Association of Adverse Effects of Medical Treatment With Mortality in the United States: A Secondary Analysis of the Global Burden of Diseases, Injuries, and Risk Factors Study

This study analyzed data from the Global Burden of Disease Study to assess mortality associated with adverse effects of medical treatment (AEMT) in the U.S. between 1990 and 2016. Findings revealed that AEMT was a significant cause of mortality, with notable increases in deaths over the study period. The analysis

June 26, 2025 No Comments

Tag: mortality