This 2013 review article examines the use of dietary supplements (DS) in oncology, highlighting that a majority of cancer patients incorporate DS into their treatment regimens. The authors discuss commonly used supplements such as curcumin, glutamine, vitamin D, Maitake mushrooms, fish oil, green tea, milk thistle, Astragalus, melatonin, and probiotics.
This narrative review discusses the hepatoprotective benefits of silymarin, an extract from milk thistle, in treating liver diseases such as cirrhosis, non-alcoholic fatty liver disease, and drug-induced liver injury. Clinical studies demonstrated that silymarin reduces oxidative stress, improves liver function, and offers potential benefits in glycemic control for patients with
This systematic review evaluates the clinical efficacy and safety of silymarin, a flavonoid complex from milk thistle, in treating liver diseases such as Amanita phalloides poisoning, alcoholic liver disease, and cirrhosis. The review analyzed 36 studies, showing that silymarin significantly reduced liver-related mortality by 7% in cirrhosis patients (p
This randomized, double-blind, placebo-controlled trial evaluated the efficacy of silymarin in patients with nonalcoholic steatohepatitis (NASH). While silymarin did not significantly reduce the NAFLD activity score (NAS) by 30% or more compared to placebo, it was associated with a significant reduction in liver fibrosis as measured by both histology and
