Well Referenced

Tag: mental fatigue

Exploratory open label, randomized study of acetyl- and propionylcarnitine in chronic fatigue syndrome

This exploratory open-label, randomized study examined the effects of acetylcarnitine and propionylcarnitine on fatigue and attention concentration in patients with chronic fatigue syndrome (CFS). Acetylcarnitine significantly improved mental fatigue (p = 0.015), while propionylcarnitine improved general fatigue (p = 0.004), with both treatments enhancing attention concentration. However, combined treatment was

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June 26, 2025 No Comments

L-carnitine supplementation for the management of fatigue in patients with hypothyroidism on levothyroxine treatment: a randomized, double-blind, placebo-controlled trial

A randomized, double-blind, placebo-controlled trial investigated the effects of L-carnitine supplementation on fatigue in hypothyroid patients undergoing levothyroxine treatment. Sixty patients (mean age 50.0 ± 9.2 years; 3 males, 57 females) experiencing persistent fatigue (Fatigue Severity Scale [FSS] score ≥36) were randomized to receive either L-carnitine (990 mg twice daily;

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June 26, 2025 No Comments