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Tag: male hypogonadism

Safety and efficacy of enclomiphene and clomiphene for hypogonadal men

This observational study compared the safety and efficacy of enclomiphene versus clomiphene in treating hypogonadal men, demonstrating that enclomiphene significantly increased testosterone levels (median increase of 166 ng/dL vs. 98 ng/dL with clomiphene) while reducing estradiol levels (5.92 pg/mL decrease vs. 17.50 pg/mL increase with clomiphene, P=0.001). Enclomiphene also had

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June 26, 2025 No Comments

Cardiovascular disease and testosterone therapy in male hypogonadism

This review evaluates the cardiovascular effects of testosterone therapy in men with hypogonadism, highlighting mixed evidence on cardiovascular risks. It suggests that testosterone therapy is generally safe for cardiovascular health, particularly in middle-aged and older men, improving metabolic profiles without increasing major cardiovascular events. The therapy does, however, elevate hematocrit

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June 26, 2025 No Comments