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Tag: magnesium supplementation

Comparison of the Efficacy of Oral versus Intravascular Magnesium in the Prevention of Hypomagnesemia and Arrhythmia after CABG

This 2018 interventional clinical study compared the effectiveness of oral versus intravenous (IV) magnesium supplementation in preventing hypomagnesemia and arrhythmias following coronary artery bypass grafting (CABG). Eighty-two patients were randomized to receive either 1,600 mg of oral magnesium hydroxide via nasogastric tube before surgery or 2 g of IV magnesium

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June 26, 2025 No Comments

Magnesium Deficiency is Associated with Periodontal Disease

This 2005 cross-sectional study analyzed data from 4,290 participants aged 20–80 years to investigate the relationship between magnesium status and periodontal health. The study found that individuals aged 40 and older with higher serum magnesium-to-calcium ratios exhibited significantly reduced probing depths (p < 0.001), less attachment loss (p = 0.006),

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June 26, 2025 No Comments

Changes of Blood Pressure and Hemodynamic Parameters after Oral Magnesium Supplementation in Patients with Essential Hypertension—An Intervention Study

This 2018 single-arm, non-blinded intervention study evaluated the effects of daily 300 mg oral magnesium oxide supplementation over one month in 48 patients with essential hypertension whose antihypertensive therapy remained unchanged. Post-intervention, significant reductions in systolic (from 139.7 ± 15.0 to 130.8 ± 13.4 mmHg) and diastolic (from 88.0 ±

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June 26, 2025 No Comments

Magnesium supplementation enhances mTOR signalling to facilitate myogenic differentiation and improve aged muscle performance

This cohort study investigated the effects of magnesium supplementation on muscle performance and myogenic differentiation in older adults. It found that magnesium supplementation enhanced mTOR signaling, which is essential for muscle protein synthesis, leading to improved muscle strength, function, and tissue regeneration in individuals aged 60-75. The supplementation significantly improved

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June 26, 2025 No Comments

On the significance of magnesium in extreme physical stress

This 1998 animal study published in the Journal of the American College of Nutrition explored the effects of magnesium deficiency on cardiovascular, metabolic, and lipid parameters in rats. Over a 21-day period, rats on a magnesium-deficient diet developed cardiac arrhythmias, impaired glucose tolerance, and significantly reduced serum cholesterol levels. The

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June 26, 2025 No Comments

The 3Mg trial: a randomised controlled trial of intravenous or nebulised magnesium sulphate versus placebo in adults with acute severe asthma

This 2014 cohort study published in the American Journal of Clinical Nutrition analyzed data from 13,504 U.S. adults in NHANES III to examine the association between magnesium intake and liver disease mortality over a follow-up period through 2006. The study found that individuals with higher magnesium intake had a significantly

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June 26, 2025 No Comments

Magnesium Restores Activity to Peripheral Blood Cells in a Patient With Functionally Impaired Interleukin-2-Inducible T Cell Kinase

This case report describes the restoration of immune function in a 24-year-old male patient with an interleukin-2-inducible T-cell kinase (ITK) gene mutation, which caused significant immune dysfunction. The patient received magnesium supplementation, which resulted in the restoration of T-cell activation and improved immune response. This study suggests that magnesium supplementation

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June 26, 2025 No Comments

Oral magnesium supplementation reduces the incidence of gastrointestinal complications following cardiac surgery: a randomized clinical trial

This randomized clinical trial examined the effects of oral magnesium supplementation (800 mg daily) on gastrointestinal complications in 102 patients undergoing coronary artery bypass graft surgery. The study found that magnesium supplementation significantly reduced the incidence of postoperative nausea, vomiting, constipation, and atrial fibrillation compared to a placebo. The intervention

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June 26, 2025 No Comments

Systemic magnesium to improve quality of post-surgical recovery in outpatient segmental mastectomy: a randomized, double-blind, placebo-controlled trial

This randomized, double-blind, placebo-controlled trial evaluated the effects of intravenous magnesium supplementation on postoperative recovery in 50 female patients undergoing outpatient segmental mastectomy. The study found that magnesium supplementation significantly improved recovery quality, reduced postoperative pain, and decreased opioid usage compared to the placebo group. Magnesium levels were notably higher

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June 26, 2025 No Comments