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Tag: low back pain

Medical Ozone as a Therapeutic Option in Musculoskeletal Pain Control: A Critical Review of Clinical Trials Considering Safety and Quality Indicators for Procedures and Devices

This critical review explores the clinical use of medical ozone therapy for managing musculoskeletal pain, such as low back pain, knee osteoarthritis, and disc herniation. It evaluates the efficacy, safety, and quality control of ozone procedures and devices across multiple clinical trials. The findings suggest that ozone therapy can significantly

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June 26, 2025 No Comments

Oxygen-Ozone Therapy in the Rehabilitation Field: State of the Art on Mechanisms of Action, Safety and Effectiveness in Patients with Musculoskeletal Disorders

This systematic review published in Biomolecules (2021) analyzes the safety, mechanisms of action, and efficacy of oxygen-ozone (O₂O₃) therapy in patients with musculoskeletal disorders, particularly low back pain and knee osteoarthritis. The therapy works by inducing moderate oxidative stress, which produces signaling molecules that modulate inflammation and oxidative stress pathways,

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June 26, 2025 No Comments