Well Referenced

Tag: IV nutrient therapy

Pharmacokinetics of glutathione and its metabolites in normal subjects

This observational study investigated the pharmacokinetics of glutathione (GSH) and its metabolites—cysteine (Cys), cystine (Cys2), and methionine (Met)—in healthy individuals to determine optimal dosing for reducing reactive oxygen species (ROS), especially in cases like paraquat poisoning. It found that Cys and Met effectively suppressed ROS production in a dose-dependent manner,

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June 26, 2025 No Comments

Feasibility of Vitamin C in the Treatment of Post Viral Fatigue with Focus on Long COVID, Based on a Systematic Review of IV Vitamin C on Fatigue

This systematic review examined the effectiveness and feasibility of high-dose intravenous (IV) vitamin C in treating fatigue, particularly in post-viral contexts such as long COVID. Across nine studies with 720 participants, three of four controlled trials and four of five observational studies showed a significant reduction in fatigue levels in

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June 26, 2025 No Comments

Combination of High-Dose Parenteral Ascorbate (Vitamin C) and Alpha-Lipoic Acid Failed to Enhance Tumor-Inhibitory Effect But Increased Toxicity in Preclinical Cancer Models

This preclinical study investigated the combined effects of high-dose intravenous vitamin C (ascorbate, Asc) and alpha-lipoic acid (ALA) on six human cancer cell lines and a mouse model of metastatic breast cancer. While high-dose Asc alone demonstrated tumor-inhibitory effects without toxicity, ALA did not inhibit tumor growth and instead increased

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June 26, 2025 No Comments

DHEA Modulates Immune Function: A Review of Evidence

The systematic review titled “DHEA Modulates Immune Function: A Review of Evidence” (Vitamins and Hormones, 2018, PMID: 30029724) explores the immunomodulatory effects of dehydroepiandrosterone (DHEA) and its potential role in enhancing immune function. The review highlights DHEA’s ability to increase cytokine production, enhance natural killer (NK) cell activity, and improve

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June 26, 2025 No Comments