Well Referenced

Tag: ischemic heart disease

Increased Cardiovascular Disease Mortality Associated With Excessive Exercise in Heart Attack Survivors

This prospective cohort study evaluated 2,377 myocardial infarction (MI) survivors over a mean follow-up of 10.4 years to examine the relationship between exercise volume and cardiovascular mortality. Findings revealed that moderate physical activity (up to 7.2 MET-hours/day) significantly reduced cardiovascular disease (CVD) mortality, with optimal benefits at 5.4–7.2 MET-h/day. However,

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June 26, 2025 No Comments

Angina in 2022: Current Perspectives

This 2022 comprehensive review re-evaluates the understanding and management of angina pectoris, noting that only around 50% of cases are due to obstructive epicardial coronary artery disease. A significant proportion is attributable to coronary vasomotor disorders, including microvascular dysfunction and epicardial coronary spasm. The article emphasizes a pathophysiology-based approach to

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June 26, 2025 No Comments

Chelation Therapy for Ischemic Heart Disease: A Randomized Controlled Trial

This multicenter randomized controlled trial investigated the effectiveness of disodium EDTA chelation therapy in patients with a history of myocardial infarction. Participants were randomized to receive either EDTA-based chelation therapy or placebo over a series of infusions. The primary composite endpoint included all-cause mortality, recurrent myocardial infarction, stroke, coronary revascularization,

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June 26, 2025 No Comments

Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis for the Global Burden of Disease Study 2013

This 2016 systematic review and dose-response meta-analysis incorporated data from 174 prospective cohort studies to evaluate the relationship between physical activity and the incidence of breast cancer, colon cancer, type 2 diabetes, ischemic heart disease, and ischemic stroke. It demonstrated an inverse, non-linear relationship between total physical activity (measured in

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June 26, 2025 No Comments

Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease

This nested case-control study in men from the Quebec Cardiovascular Study identified fasting plasma insulin levels, apolipoprotein B, and small, dense LDL particles as significant independent risk factors for ischemic heart disease (IHD), with an odds ratio of 5.9 (95% CI, 2.3-15.4). The findings suggest that these nontraditional metabolic markers,

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June 26, 2025 No Comments

Coenzyme Q10 as Adjunctive Therapy for Cardiovascular Disease and Hypertension: A Systematic Review

This systematic review analyzed 14 studies involving 1,067 predominantly older adult males and evaluated the effectiveness of Coenzyme Q10 (CoQ10) as adjunctive therapy in patients with cardiovascular disease (CVD) and hypertension. Findings indicated that CoQ10 supplementation improved functional capacity in heart failure patients, increased serum CoQ10 levels, reduced major cardiovascular

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June 26, 2025 No Comments