Well Referenced

Tag: intravenous therapy

Corrigendum to “A pilot study for treatment of COVID-19 patients in moderate stage using intravenous administration of ozonized saline as an adjuvant treatment-registered clinical trial”

This corrigendum, published in 2022, addresses corrections to the original 2021 pilot study that evaluated intravenous ozonized saline as an adjunctive treatment for moderate COVID-19 cases. While the specific corrections are not detailed in the available abstract, such corrigenda typically involve amendments to data, authorship, or methodological details. The original

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June 26, 2025 No Comments

Treatment for Diabetic Mononeuropathy with Alpha-Lipoic Acid

This clinical study evaluated the efficacy of alpha-lipoic acid (ALA) in treating diabetic mononeuropathy. Patients received 600 mg of ALA intravenously daily for 10 days, followed by 600 mg orally daily for approximately 69 days. Results demonstrated significant symptom improvement: total symptom scores decreased by an average of 2.7 points

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June 26, 2025 No Comments

The Controversial Place of Vitamin C in Cancer Treatment

This 2008 review critically examines the role of vitamin C in cancer therapy. While early studies, notably by Linus Pauling, suggested benefits of high-dose vitamin C, subsequent randomized trials using oral administration did not confirm these findings. Recent pharmacokinetic data indicate that intravenous vitamin C can achieve plasma concentrations with

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June 26, 2025 No Comments

The Effect of High Dose Intravenous Vitamin C During Radiotherapy on Breast Cancer Patients’ Neutrophil-Lymphocyte Ratio

This 2020 retrospective observational study assessed the impact of high-dose intravenous vitamin C (IVC) on the neutrophil-lymphocyte ratio (NLR) in 424 breast cancer patients undergoing postoperative radiotherapy. Patients were divided into three groups: control (no IVC), low-dose IVC (1 g/kg). NLR, a marker of systemic inflammation linked to cancer prognosis,

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June 26, 2025 No Comments

High-Dose Vitamin C Promotes Regression of Multiple Pulmonary Metastases Originating from Hepatocellular Carcinoma

This 2015 case report details a 74-year-old woman with hepatocellular carcinoma (HCC) who experienced regression of multiple pulmonary metastases following intravenous high-dose vitamin C therapy. After initial transarterial chemoembolization (TACE), she developed recurrent HCC with lung metastases and declined further conventional treatment. She received 70 g of intravenous vitamin C

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June 26, 2025 No Comments

Ocular Side Effects of Bisphosphonates: A Review of Literature

This 2023 review analyzed 101 reports of bisphosphonate-associated ocular complications, including uveitis, scleritis, episcleritis, conjunctivitis, and orbital inflammation. These adverse effects are primarily linked to second- and third-generation amino bisphosphonates such as alendronate, pamidronate, risedronate, and zoledronate, with intravenous forms posing a higher risk and more rapid onset than oral

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June 26, 2025 No Comments

High-dose intravenous glutathione in man. Pharmacokinetics and effects on cyst(e)ine in plasma and urine

This randomized, double-blind, placebo-controlled trial evaluated the effects of intravenous glutathione in 30 patients with alcoholic liver disease (ALD). Patients treated with glutathione showed statistically significant improvements in liver enzyme levels—specifically reductions in GGT, AST, and ALT—indicating reduced liver inflammation and oxidative stress. The therapy was well-tolerated, with no significant

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June 26, 2025 No Comments

History of Chelation Therapy

Chelation therapy, developed in the 1930s with the synthesis of EDTA, was initially used during World War II to treat heavy metal poisoning. In the 1950s, it was observed that patients receiving chelation therapy for lead poisoning experienced improvements in conditions like angina pectoris, suggesting potential cardiovascular benefits. Over time,

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June 26, 2025 No Comments