Well Referenced

Tag: Hemoglobin

Treatment efficacy of vitamin C or ascorbate given as co-intervention with iron for anemia – A systematic review and meta-analysis of experimental studies

This 2023 systematic review and meta-analysis evaluated the efficacy of combining oral vitamin C (ascorbic acid) with iron supplementation in treating anemia. Analyzing nine studies (seven included in meta-analysis) encompassing 905 participants with laboratory-confirmed anemia, the study compared outcomes between groups receiving iron plus vitamin C versus iron alone. The

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June 26, 2025 No Comments

Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical trials

This systematic review and meta-analysis evaluated the efficacy and safety of intravenous (IV) iron therapy in reducing the need for allogeneic red blood cell transfusions. The analysis included 72 randomized controlled trials encompassing 10,605 patients. Findings demonstrated that IV iron therapy significantly increased hemoglobin levels (standardized mean difference of 6.5

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June 26, 2025 No Comments

Comparative safety of intravenous ferumoxytol versus ferric carboxymaltose in iron deficiency anemia: A randomized trial

This randomized, multicenter, double-blind clinical trial assessed the safety and efficacy of intravenous ferumoxytol compared to ferric carboxymaltose (FCM) in patients with iron deficiency anemia (IDA) unresponsive or intolerant to oral iron. A total of 1,997 patients received either ferumoxytol (n=997) or FCM (n=1000) over ≥15 minutes on days 1

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June 26, 2025 No Comments

Ozone Therapy for Tumor Oxygenation: a Pilot Study

This 2004 pilot study evaluated the impact of systemic ozone therapy on tumor oxygenation in 18 patients with advanced cancers. Administered via autohemotransfusion over one week, ozone therapy did not significantly alter overall tumor oxygenation levels. However, it notably reduced the proportion of severely hypoxic tumor regions (pO₂ ≤10 mmHg

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June 26, 2025 No Comments

Anemia in Older Adults

This review article discusses the evaluation and management of anemia in older adults, a condition associated with increased morbidity and mortality. It highlights that anemia is frequently asymptomatic but can present with fatigue, weakness, or shortness of breath. Common causes include iron deficiency, chronic kidney disease, inflammation, and gastrointestinal blood

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June 26, 2025 No Comments

Blood donation and testosterone replacement therapy

This observational study examined the impact of testosterone replacement therapy (TRT) on hemoglobin levels in 39 male blood donors, revealing that 25% of clinic visits recorded hemoglobin levels ≥180 g/L, and 44% of repeat donors had persistently elevated levels. This suggests that blood donation alone may be insufficient to manage

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June 26, 2025 No Comments