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Tag: heavy metal poisoning

DMSA and DMPS–water soluble antidotes for heavy metal poisoning

This review article discusses the use of DMSA (dimercaptosuccinic acid) and DMPS (dimercaptopropanesulfonate) as safe and effective water-soluble chelating agents for treating heavy metal poisoning, including lead, mercury, arsenic, and cadmium. Both agents are shown to be effective in promoting the excretion of toxic metals while having minimal side effects

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June 26, 2025 No Comments

Lead induced oxidative stress and its recovery following co-administration of melatonin or N-acetylcysteine during chelation with succimer in male rats

This study examined the effectiveness of melatonin and N-acetylcysteine (NAC), both alone and in combination with the chelating agent meso 2,3-dimercaptosuccinic acid (DMSA), in mitigating lead-induced oxidative stress in male rats. The research evaluated reductions in lead concentrations in blood and soft tissues, as well as the restoration of hematopoietic,

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June 26, 2025 No Comments