Well Referenced

Tag: Genotoxicity

CaNa2EDTA chelation attenuates cell damage in workers exposed to lead–a pilot study

This 2015 pilot study investigated the effects of CaNa₂EDTA chelation therapy on oxidative and genotoxic damage in smelting factory workers with chronic lead exposure averaging 5.8 ± 1.2 years. Following a five-day CaNa₂EDTA regimen, significant reductions were observed in oxidative stress biomarkers, including normalized activities of antioxidant enzymes (Cu,Zn-SOD and

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June 26, 2025 No Comments

Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial

This pilot clinical trial investigated the effects of GlyNAC supplementation (a combination of glycine and N-acetylcysteine) in older adults over a 24-week period. The study found that GlyNAC supplementation corrected intracellular glutathione deficiency, reduced oxidative stress, improved mitochondrial function, decreased inflammation, enhanced insulin sensitivity, ameliorated endothelial dysfunction, reduced genomic damage,

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June 26, 2025 No Comments