Tag: gastrointestinal disorders

Magnesium Orotate and the Microbiome-Gut-Brain Axis Modulation: New Approaches in Psychological Comorbidities of Gastrointestinal Functional Disorders

This study investigates the potential therapeutic effects of magnesium orotate in modulating the microbiome-gut-brain axis in individuals with gastrointestinal (GI) functional disorders and comorbid psychological symptoms, such as anxiety and depression. The cohort study involving 150 participants found that magnesium orotate improved both GI symptoms and psychological distress, suggesting a

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Glutamine Supplementation as a Novel Metabolic Therapeutic Strategy for LIG3-Dependent Chronic Intestinal Pseudo-Obstruction

The 2025 study “Glutamine Supplementation as a Novel Metabolic Therapeutic Strategy for LIG3-Dependent Chronic Intestinal Pseudo-Obstruction” explores glutamine as a therapeutic approach for treating chronic intestinal pseudo-obstruction (CIPO) caused by LIG3 mutations. The study finds that glutamine supplementation improves intestinal motility, reduces symptoms such as bloating and constipation, and enhances

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