Well Referenced

Tag: gas chromatography-mass spectrometry

Cytotoxic Effects of the Viscum Album L. Extract on Ehrlich Tumour Cells in Vivo

This in vivo animal study investigated the cytotoxic effects of non-polar constituents from Viscum album L. (European mistletoe) on Ehrlich ascites carcinoma (EAC) cells in mice. Extracted using supercritical CO₂ and analyzed by GC/MS, the mistletoe contained novel terpenes that, when administered before and after tumor cell inoculation, significantly reduced

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June 26, 2025 No Comments

Pregnenolone and dehydroepiandrosterone as precursors of native 7-hydroxylated metabolites which increase the immune response in mice

This study investigated the metabolism of dehydroepiandrosterone (DHEA) and pregnenolone (PREG) in various mouse tissues and their effects on immune response. Using deuterium-labeled substrates and gas chromatography-mass spectrometry, researchers identified 7α-hydroxy-DHEA and 5-androstene-3β,17β-diol as DHEA metabolites across all tested tissues, while PREG metabolism was less extensive, with 7α-hydroxy-PREG found in

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June 26, 2025 No Comments