Well Referenced

Tag: fractures

Testosterone Treatment and Fractures in Men with Hypogonadism

A randomized controlled trial published in the New England Journal of Medicine examined the effects of testosterone therapy on fracture risk in men with hypogonadism. The study included 5,204 men aged 45 to 80 with hypogonadism and cardiovascular risk factors, who were randomized to receive either testosterone gel or placebo

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June 26, 2025 No Comments

Estrogen and bones after menopause: a reappraisal of data and future perspectives

This review article examines the role of estrogen-based menopausal hormone therapy (MHT) in preventing postmenopausal bone loss and reducing fracture risk by exploring its dual mechanisms—suppressing osteoclast activity and enhancing osteoblast function—in a dose-dependent manner, with benefits seen even at ultra-low doses and through transdermal delivery. It discusses the clinical

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June 26, 2025 No Comments