Tag: fasting insulin

Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease

This nested case-control study in men from the Quebec Cardiovascular Study identified fasting plasma insulin levels, apolipoprotein B, and small, dense LDL particles as significant independent risk factors for ischemic heart disease (IHD), with an odds ratio of 5.9 (95% CI, 2.3-15.4). The findings suggest that these nontraditional metabolic markers,

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Testosterone therapy reduces insulin resistance in men with adult-onset testosterone deficiency and metabolic syndrome. Results from the Moscow Study, a randomized controlled trial with an open-label phase

Testosterone therapy was found to significantly reduce insulin resistance in men with metabolic syndrome (MetS) and hypogonadism, particularly in those not receiving antiglycaemic therapy. The study, a randomized controlled trial, included 184 men, with 113 receiving testosterone undecanoate (TU) and 71 receiving placebo. Results showed a significant reduction in HOMA-IR,

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Effects of growth hormone–releasing hormone on cognitive function in adults with mild cognitive impairment and healthy older adults: results of a controlled trial

A randomized controlled trial published in Archives of Neurology (PMID: 22869065) examined the effects of growth hormone–releasing hormone (GHRH) on cognitive function in adults with mild cognitive impairment (MCI) and healthy older adults. Over 20 weeks, participants received daily subcutaneous injections of GHRH or a placebo. The study found that

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