Well Referenced

Tag: Erectile dysfunction

Treatment of Diabetic Impotence with Umbilical Cord Blood Stem Cell Intracavernosal Transplant: Preliminary Report of 7 Cases

This 2010 pilot study assessed the safety and efficacy of intracavernosal injections of human umbilical cord blood stem cells (hUCBSCs) in seven male patients (ages 57–87) with type 2 diabetes mellitus and refractory erectile dysfunction (ED). Each patient received a single injection of 1.5×10⁷ hUCBSCs without immunosuppression. Over a 9-month

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June 26, 2025 No Comments

Erectile Dysfunction Treatment Using Stem Cells: A Review

This 2021 systematic review evaluated clinical studies on stem cell therapy (SCT) for erectile dysfunction (ED), highlighting its potential as a regenerative treatment. Various stem cell types—adipose-derived (ADSC), bone marrow-derived (BMSC), umbilical cord, and placental—have been administered primarily via intracavernosal injection. Clinical trials reported improvements in erectile function, with some

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June 26, 2025 No Comments

Effects of Stem Cell Treatment in Human Patients With Peyronie Disease

This prospective pilot study evaluated the safety and efficacy of intracavernosal injections of placental matrix-derived mesenchymal stem cells (PM-MSCs) in five male patients aged 45–59 with Peyronie’s disease (PD). Patients received a single PM-MSC injection and were followed at 6 weeks, 3 months, and 6 months. Significant improvements were observed

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June 26, 2025 No Comments

The Current Status of Stem-Cell Therapy in Erectile Dysfunction: A Review

This 2016 review by Reed-Maldonado and Lue examines the application of stem cell (SC) therapy for erectile dysfunction (ED). The authors discuss various types of stem cells, including adipose-derived, bone marrow-derived, and umbilical cord-derived stem cells, and their potential mechanisms in treating ED. The review highlights four clinical trials where

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June 26, 2025 No Comments

Penile low intensity shock wave treatment for PDE5I refractory erectile dysfunction: a randomized double-blind sham-controlled clinical trial

This randomized, double-blind, sham-controlled clinical trial assessed the efficacy of low-intensity extracorporeal shockwave therapy (LI-ESWT) in 76 men with vascular erectile dysfunction (ED) unresponsive to phosphodiesterase type 5 inhibitors (PDE5Is). Participants received weekly sessions for four weeks (5000 shocks/session at 0.09 mJ/mm²). At 3 months, the treatment group showed a

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June 26, 2025 No Comments

Availability of platelet-rich plasma for treatment of erectile dysfunction and associated costs and efficacy: A review of current publications and Canadian data

This 2021 review assessed the availability, cost, and clinical evidence of platelet-rich plasma (PRP) therapy for erectile dysfunction (ED) in Canada. The authors identified 19 Canadian providers offering PRP injections for ED, with an average cost of $1,777 CAD per injection. None of these providers were affiliated with academic institutions,

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June 26, 2025 No Comments

Functional and quality of life outcomes of localised prostate cancer treatments (Prostate Testing for Cancer and Treatment [ProtecT] study)

This large-scale longitudinal study assessed the functional and quality of life outcomes in 2,565 men aged 50–69 with localized prostate cancer, randomized to active monitoring (AM), radical prostatectomy (RP), external-beam radiotherapy (EBRT) with androgen deprivation therapy (ADT), or low-dose-rate brachytherapy (BT). Over six years, AM was associated with gradual declines

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June 26, 2025 No Comments

Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use

This 2023 systematic review and meta-analysis evaluated the efficacy of dietary supplements (DSs) for erectile dysfunction (ED). The study analyzed DSs marketed in Italy, assessing their active ingredients and dosages against evidence-based minimal effective daily doses (mEDs). Among 25 products, only 2 (8%) matched the higher expected efficacy cluster, 3

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June 26, 2025 No Comments