Well Referenced

Tag: endocrine disruptors

Exposures, Mechanisms, and Impacts of Endocrine-Active Flame Retardants

This 2014 review examines the endocrine and neurodevelopmental effects of flame retardants, focusing on tris(1,3-dichloro-isopropyl) phosphate (TDCPP), Firemaster® 550 (FM550), and polybrominated diphenyl ethers (PBDEs). These chemicals, commonly used in consumer products like polyurethane foam, have led to widespread indoor exposure. PBDEs and their metabolites primarily disrupt thyroid function due

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June 26, 2025 No Comments

Diet: A Source of Endocrine Disruptors

This 2020 review examines how common dietary sources contribute to human exposure to endocrine-disrupting chemicals (EDCs). It highlights that food is a significant route of EDC exposure, with substances like bisphenol A (BPA), phthalates, and persistent organic pollutants (POPs) present in various food items. These chemicals can interfere with hormonal

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June 26, 2025 No Comments

What you extract is what you see: Optimising the preparation of water and wastewater samples for in vitro bioassays

This 2019 study by Abbas et al. evaluated how different sample preparation methods impact the outcomes of in vitro bioassays used for water quality assessment. Researchers tested surface water, groundwater, hospital, and municipal wastewater using 11 bioassays targeting endocrine activity, mutagenicity, genotoxicity, and cytotoxicity. They compared solid-phase extraction (SPE) methods

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June 26, 2025 No Comments

Metals and breast cancer

This 2013 review explores the role of metalloestrogens—metals that can activate estrogen receptors—in breast cancer development. It highlights cadmium as a well-studied example, demonstrating its ability to mimic estrogen and promote tumor growth. The review discusses how these metals, including cadmium, arsenite, and others, can bind to estrogen receptor-α, leading

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June 26, 2025 No Comments

A Brief Look at Hashimoto’s Disease, Adrenal Incidentalomas, Obesity and Insulin Resistance-Could Endocrine Disruptors Be the Other Side of the Same Coin?

This study explores the potential connection between endocrine disruptors and the increasing prevalence of Hashimoto’s disease, adrenal incidentalomas, obesity, and insulin resistance. It suggests that these conditions may share common environmental triggers, particularly exposure to hormonally active substances that interfere with endocrine function. The research underscores the need for further

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June 26, 2025 No Comments