This 2020 review examines how common dietary sources contribute to human exposure to endocrine-disrupting chemicals (EDCs). It highlights that food is a significant route of EDC exposure, with substances like bisphenol A (BPA), phthalates, and persistent organic pollutants (POPs) present in various food items. These chemicals can interfere with hormonal
This systematic review and meta-analysis evaluated eight randomized controlled trials involving 1,022 overweight or obese adults (BMI ≥25) to compare the effectiveness of combined behavioral weight management programs (BWMPs) incorporating both diet and physical activity versus diet-only or physical activity-only interventions. Short-term (3–6 months) weight loss was similar between combined
This 2014 randomized controlled trial examined the effects of an 8-week intervention involving diet alone, diet plus strength training, or diet plus aerobic training in 81 overweight and obese adults. All participants followed a hypocaloric formula diet providing 70% of their resting metabolic rate. Exercise groups trained three times per
This 2011 randomized controlled trial assessed the impact of omega-3 fatty acid supplementation combined with dietary and exercise counseling on weight loss and body composition in overweight and obese adults. Over 24 weeks, participants in both the omega-3 and placebo groups lost more than 5% of their body weight. However,
This 2005 randomized, controlled trial assessed the efficacy of combining sibutramine (15 mg daily) with lifestyle modification in 224 obese adults over one year. Participants were assigned to one of four groups: sibutramine alone, lifestyle modification alone, sibutramine plus lifestyle modification, or sibutramine plus brief lifestyle counseling. All groups followed
This 2013 review evaluates the evidence linking dietary habits to the development and progression of prostate cancer. It identifies high intake of animal fats, red meat, and dairy products as significant dietary risk factors, while plant-based diets rich in vegetables, fruits, and whole grains may reduce prostate cancer risk. The
This comprehensive review highlights a significant global increase in early-onset cancers (diagnosed before age 50), including breast, colorectal, endometrial, and pancreatic cancers. While improved screening contributes to some cases, a genuine rise is attributed to early-life exposures such as dietary changes, obesity, sedentary lifestyles, environmental toxins, and microbiome alterations. The
This comprehensive review emphasizes that a significant proportion of cancer cases are preventable through lifestyle modifications. The authors estimate that approximately 30–35% of cancer-related deaths are linked to dietary factors, 25–30% to tobacco use, 15–20% to infections, and the remainder to other factors such as physical inactivity, environmental pollutants, and
This 2021 review examines the role of various dietary factors in the development, progression, and potential reduction of prostate cancer (PCa). High intake of red and processed meats, saturated fats, and dairy products is associated with increased PCa risk. Conversely, diets high in fruits, vegetables, legumes, and whole grains, especially
This comprehensive review highlights the critical role of oxidative stress and inflammation in the pathogenesis of erectile dysfunction (ED) and vascular diseases, primarily through the disruption of nitric oxide (NO) production. Key lifestyle interventions include regular physical activity, weight loss, and dietary modifications to reduce fat and sugar intake, all
