Well Referenced

Tag: coronary heart disease

Hormone replacement therapy and the association with coronary heart disease and overall mortality: clinical application of the timing hypothesis

This article reviews the benefits of hormone replacement therapy (HRT) for postmenopausal women, specifically in reducing the risk of coronary heart disease (CHD) and improving overall mortality. The study supports the “timing hypothesis,” indicating that initiating HRT shortly after menopause (within 10 years or before age 60) provides significant benefits,

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June 26, 2025 No Comments

Inflammatory biomarkers, hormone replacement therapy, and incident coronary heart disease: prospective analysis from the Women’s Health Initiative observational study

This cohort study, conducted within the Women’s Health Initiative, examined the relationship between inflammatory biomarkers, hormone replacement therapy (HRT), and coronary heart disease (CHD) risk in postmenopausal women. Among 304 CHD cases and 304 matched controls, elevated baseline levels of C-reactive protein (CRP) and interleukin-6 (IL-6) were significantly associated with

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June 26, 2025 No Comments

Baseline associations between postmenopausal hormone therapy and inflammatory, haemostatic, and lipid biomarkers of coronary heart disease. The Women’s Health Initiative Observational Study

This study from the Women’s Health Initiative Observational Study examined how postmenopausal hormone therapy (PHT) affects biomarkers associated with coronary heart disease (CHD). Results showed that PHT use is linked to increased CRP, HDL, and triglyceride levels, as well as lower tPA-antigen and homocysteine. Estrogen plus progestin use was associated

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June 26, 2025 No Comments