Tag: copper overload

Chelation in metal intoxication–Principles and paradigms

This review article discusses the role of chelation therapy in treating metal intoxication, focusing on the advancements and use of newer, less toxic chelating agents like DMSA and DMPS, which are effective for treating heavy metal poisoning and available in oral form. It highlights DMSA’s potency in treating copper overload

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Chelation therapy in intoxications with mercury, lead and copper

This systematic review examines the role of chelation therapy in the treatment of mercury, lead, and copper intoxications, highlighting newer chelating agents such as meso-2,3-dimercaptosuccinic acid (DMSA) and 2,3-dimercapto-propanesulphonate (DMPS), which have a safer profile compared to older agents like dimercaptopropanol (BAL). The review also discusses the use of D-penicillamine

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