Well Referenced

Tag: conjugated equine estrogens

The effect of medroxyprogesterone acetate on estrogen-dependent risks and benefits–an attempt to interpret the Women’s Health Initiative results

A review published in Gynecological Endocrinology analyzed the Women’s Health Initiative (WHI) findings on hormone replacement therapy (HRT) in postmenopausal women, focusing on the effects of conjugated equine estrogens (CEE) alone versus CEE combined with medroxyprogesterone acetate (MPA). The study highlighted that the high prevalence of metabolic syndrome among participants

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June 26, 2025 No Comments

Effects of oral versus transdermal menopausal hormone treatments on self-reported sleep domains and their association with vasomotor symptoms in recently menopausal women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS)

This randomized controlled trial, published in Menopause in 2018 (PMID: 28832429), examined the effects of oral conjugated equine estrogens (o-CEE) and transdermal estradiol (t-E2) on sleep quality in recently menopausal women as part of the Kronos Early Estrogen Prevention Study (KEEPS). Both hormone treatments significantly improved global Pittsburgh Sleep Quality

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June 26, 2025 No Comments