Well Referenced

Tag: cardiovascular risk factors

Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values’

This multicenter European study aimed to establish reference and normal values for carotid-femoral pulse wave velocity (cf-PWV), a direct measure of aortic stiffness, by analyzing data from 16,867 subjects across 13 centers in eight countries. Among these, 11,092 individuals without overt cardiovascular disease, diabetes, or antihypertensive/lipid-lowering treatment constituted the reference

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June 26, 2025 No Comments

Relations of plasma high-sensitivity C-reactive protein to traditional cardiovascular risk factors

This observational study, published in Atherosclerosis (DOI: 10.1016/s0021-9150(02)00380-5), explored the relationship between plasma high-sensitivity C-reactive protein (hsCRP) levels and traditional cardiovascular risk factors in 908 participants aged 30-79. The study found that hsCRP levels were significantly higher in individuals with hypertension, diabetes, or coronary artery disease, and multiple regression analysis

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June 26, 2025 No Comments

The association between homocysteine and myocardial infarction is independent of age, sex, blood pressure, cholesterol, smoking and markers of inflammation: the Glasgow Myocardial Infarction Study

This case-control study from the Glasgow Myocardial Infarction Study evaluated the association between plasma homocysteine levels and myocardial infarction (MI) in 712 MI patients and 697 age- and sex-matched controls. Results showed that elevated homocysteine levels were significantly associated with nearly double the risk of MI (OR 1.9; 95% CI:

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June 26, 2025 No Comments

Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease

This nested case-control study in men from the Quebec Cardiovascular Study identified fasting plasma insulin levels, apolipoprotein B, and small, dense LDL particles as significant independent risk factors for ischemic heart disease (IHD), with an odds ratio of 5.9 (95% CI, 2.3-15.4). The findings suggest that these nontraditional metabolic markers,

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June 26, 2025 No Comments

Sildenafil citrate for erectile dysfunction in men with diabetes and cardiovascular risk factors: a retrospective analysis of pooled data from placebo-controlled trials

This meta-analysis evaluated the efficacy and safety of sildenafil citrate in men with erectile dysfunction (ED) and diabetes mellitus (DM), including those with additional cardiovascular (CV) risk factors. The study pooled data from 11 randomized, double-blind, placebo-controlled trials involving 974 men with DM and ED, randomized to receive either placebo

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June 26, 2025 No Comments