Tag: Cancer Metabolism

Targeting the Mitochondrial-Stem Cell Connection in Cancer Treatment: A Hybrid Orthomolecular Protocol

This review article introduces the mitochondrial-stem cell connection (MSCC) theory, suggesting that cancer originates from chronic oxidative phosphorylation (OxPhos) dysfunction in stem cells, leading to the formation of cancer stem cells (CSCs). The proposed hybrid orthomolecular protocol integrates orthomolecules (e.g., vitamins C and D, zinc), repurposed drugs (e.g., ivermectin, benzimidazoles),

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α-Lipoic acid inhibits human lung cancer cell proliferation through Grb2-mediated EGFR downregulation

The study titled “α-Lipoic acid inhibits human lung cancer cell proliferation through Grb2-mediated EGFR downregulation” (Biochem Biophys Res Commun, 2017, PMID: 28993193) is an in vitro/animal study investigating the effects of α-lipoic acid (α-LA) on non-small cell lung cancer (NSCLC) cells. The findings indicate that α-LA suppresses NSCLC cell proliferation

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