Well Referenced

Tag: Adaptive immunity

Effects of Orally Administered Yeast-Derived Beta-Glucans: A Review

This 2014 review examines the immunomodulatory effects of orally administered yeast-derived beta-glucans (Y-BG). Despite low systemic absorption, Y-BG interacts with intestinal immune cells via receptors like Dectin-1 and CR3, enhancing both innate and adaptive immunity. Clinical studies indicate benefits such as reduced upper respiratory tract infections in susceptible individuals, increased

Read More »
June 26, 2025 No Comments

Immune-modulatory Effects of Dietary Yeast Beta-1,3/1,6-D-glucan

This 2014 review evaluates the immunomodulatory properties of dietary yeast-derived β-1,3/1,6-D-glucan, focusing on its oral bioactivity and clinical relevance. Despite low systemic absorption, oral β-glucans interact with intestinal immune cells via receptors like Dectin-1, CR3, and TLRs, leading to enhanced innate and adaptive immune responses. Clinical trials with insoluble yeast

Read More »
June 26, 2025 No Comments

Effects of Beta-Glucans on the Immune System

This 2007 review article explores the immunomodulatory properties of β-glucans, naturally occurring polysaccharides found in the cell walls of fungi, bacteria, and cereals. The authors discuss how β-glucans enhance host immune defense by activating the complement system and enhancing the function of macrophages and natural killer (NK) cells. The article

Read More »
June 26, 2025 No Comments

The Effects of Beta-Glucan on Human Immune and Cancer Cells

This review explores the immunomodulatory and potential anti-cancer effects of β-glucans, complex polysaccharides found in the cell walls of fungi, bacteria, and cereals. β-glucans interact with immune receptors such as Dectin-1, complement receptor 3 (CR3), and Toll-like receptors (TLR-2/6), activating immune cells including macrophages, neutrophils, monocytes, natural killer (NK) cells,

Read More »
June 26, 2025 No Comments

The Aging Bone Marrow and Its Impact on Immune Responses in Old Age

This review examines how aging affects bone marrow (BM) function and its role in maintaining immunological memory. Aging leads to a decline in hematopoietic stem cell function, skewing differentiation towards myeloid over lymphoid lineages, resulting in reduced production of naïve T and B cells. Additionally, the BM microenvironment undergoes changes,

Read More »
June 26, 2025 No Comments

Ironing out the role of ferroptosis in immunity

This 2024 review article delves into the intricate relationship between ferroptosis—a regulated, iron-dependent form of cell death—and the immune system. It highlights how ferroptosis influences both innate and adaptive immunity, affecting processes such as infection response, autoimmunity, and tumor immunity. The review discusses the dual role of ferroptosis in promoting

Read More »
June 26, 2025 No Comments