This review examines how oxidative stress, primarily caused by UV exposure, contributes to skin aging, including the degradation of collagen and the formation of reactive oxygen and nitrogen species. It emphasizes the skin’s adaptive response to oxidative stress and the role of antioxidants in mitigating damage. Understanding these mechanisms is
This systematic review examines the impact of vitamins and minerals on hair loss, emphasizing the importance of nutrients like iron, zinc, and vitamins A, B, C, D, and E. Deficiencies in these micronutrients can contribute to alopecia, and correcting them may help prevent or treat hair loss. The review suggests
This study examined the impact of biotin on brittle nails and onychoschizia, revealing that biotin supplementation resulted in a 25% increase in nail thickness and improved surface appearance, reducing brittleness. The research involved 32 participants, including 10 controls and 8 biotin-treated patients. Biotin enhances keratin production, improving nail health without
This randomized controlled trial examined the effects of LED phototherapy on skin rejuvenation in 76 patients with facial wrinkles, comparing 830 nm LED alone, 633 nm LED alone, a combination of both, and a placebo. Treatments were applied twice weekly for four weeks, with assessments including clinical evaluations, profilometry, histology,
This study tested the effects of daily oral collagen supplementation combined with vitamins and bioactive compounds on skin elasticity and joint health. Participants aged 35-65 showed significant improvement in skin elasticity (p
This systematic review evaluated the efficacy of biotin supplementation for hair and nail growth, analyzing 18 case reports involving patients with conditions such as biotinidase deficiency, uncombable hair syndrome, and brittle nail syndrome. All cases showed clinical improvement with biotin supplementation, but there is no strong evidence supporting its routine
This in vitro study explored the anti-aging effects of L-carnitine (LC) on adipose tissue-derived mesenchymal stem cells (ADSCs), demonstrating that LC significantly increased telomerase activity, reduced cellular senescence, and altered the methylation status of CpG islands in the hTERT promoter, which regulates telomerase expression. These findings suggest LC could enhance
This randomized controlled trial investigated the effects of biotin and dexpanthenol injections in treating diffuse hair loss. Over six weeks, both treatments showed significant improvement in hair density and reduced hair fall (p
This review examines the role of glutathione as a skin-lightening agent, focusing on its mechanism of action, efficacy, and safety. Glutathione inhibits tyrosinase, shifting melanin production from eumelanin (darker pigment) to pheomelanin (lighter pigment), and is available in oral, topical, and intravenous forms. While three randomized controlled trials suggest that
