The Female Sexual Response: Current Models, Neurobiological Underpinnings and Agents Currently Approved or Under Investigation for the Treatment of Hypoactive Sexual Desire Disorder

A systematic review examined the neurobiological mechanisms behind hypoactive sexual desire disorder (HSDD) in women, focusing on the balance between excitatory and inhibitory pathways. The study highlighted the roles of various neuromodulators, such as norepinephrine, dopamine, oxytocin, and serotonin, in sexual desire. Treatments like buspirone, bupropion, and bremelanotide aim to