This 2024 study by Liang et al. investigates the therapeutic potential of nicotinamide mononucleotide (NMN) in mitigating airway epithelial barrier dysfunction in asthma. Utilizing both in vitro and in vivo models, the researchers demonstrated that NMN supplementation enhances NAD+ levels, leading to the inhibition of SIRT3 SUMOylation. This inhibition restores
