This animal study investigated the effects of Melanotan-II (MT-II), a melanocortin receptor agonist, on penile erection in anesthetized rats. MT-II induced penile erections in a dose-dependent manner through intravenous, intrathecal, and intracavernous administration. Specifically, intravenous administration at a dose of 1 mg/kg increased the amplitude of erectile responses elicited by
