Increased gut permeability and bacterial translocation are associated with fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome: implications for disease-related biomarker discovery

This 2023 observational study published in Frontiers in Immunology (PMID: 37744357) examined the link between intestinal permeability, bacterial translocation, and the presence of fibromyalgia (FM) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). In 78 participants (22 FM, 30 ME/CFS, 26 healthy controls), FM patients showed significantly elevated plasma levels of anti-beta-lactoglobulin