This 2020 single-arm, 16-week pre-post study evaluated the NC Gut Relief Formula—a multi-ingredient herbal and nutritional supplement containing curcumin, Aloe vera, slippery elm, guar gum, pectin, peppermint oil, and glutamine—in 43 Australian adults with chronic digestive symptoms. Participants consumed 5 g/day for 4 weeks, then 10 g/day for 4 weeks.